Natural Products and Pathological Changes Prevention
An imbalance between radicals and anti-radicals capacity has been proposed to play an important role in the progression of pathological changes. Oxidative stress is considered a major contributor to various pathologies with serious public health implications such as cardiovascular disease, neurodegenerative disease and cancer. Glutathione is a crucial role in oxidative detoxification. The ratio of reduced glutathione (GSH) to oxidized glutathione (GSSH) is involved in metabolic regulation. The GSH/GSSG ratio decreases during normal aging and is further depleted in pathological tissues.
I am interested in the research on Thai natural nutrition to increase the GSH/GSSG ratio conceivably could be used to promote healthy aging and as therapeutics for chronic diseases.
Research fields:
- Phytochemicals and antioxidation of Thai natural plants
- GSH/GSSG ratio and pathological tissues
- Immunohistochemistry in pathological tissues
- Toxicological pathology
|