Mahidol University Department of Biotechnology Faculty of Science

Dr. Narupat Hongdilokkul

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Dr. Narupat Hongdilokkul received his bachelor's degree in biotechnology with first-class honors from Mahidol University in 2005. Throughout his four years as an undergraduate student, he carried out a number of research projects in different laboratories and was awarded two scholarships. After finishing his undergraduate study, he received a Japanese Government scholarship to join the international biotechnology program at Osaka University, Japan. His research work under the supervision of Prof. Shigenori Kanaya focused on the interaction between two human nuclear receptors. He completed his master's degree in 2007. He later won a Royal Thai Government scholarship and decide to pursue his doctoral study in the biomolecular structure and mechanism program at ETH Zurich, Switzerland. There he worked on directed evolution of chorismate mutases in the laboratory of Prof. Donald Hilvert. Using a genetic complementation approach, he investigated the biochemical and biophysical basis of enzyme evolvability. Dr. Narupat was awarded a doctoral degree in 2014. Before coming back to Thailand, he moved to the US to take up a postdoctoral position in the group of Prof. Floyd Romesberg at the Scripps Research Institute in La Jolla, CA. There he sought to expand the repertoire of nucleic acids and generate aptamers from unnatural building blocks. Currently, Dr. Hongdilokkul is a lecturer at the Department of Biotechnology, Faculty of Science, Mahidol University. His laboratory focuses on engineering biological macromolecules and microbes for medical and industrial applications.He is interested in harnessing the power of directed evolution and synthetic biology to generate enzymes and microbes with novel properties.

Dr. Thawatchai Chaijarasphong

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Dr. Thawatchai Chaijarasphong received his PhD in Chemistry (Chemical Biology Program) from the University of California, Berkeley, under the tutelage of Professor David Savage. His PhD dissertation, entitled Towards an In Vitro Reconstitution of Alpha-Carboxysomes, involves the use of techniques in the fields of molecular biology, microbiology, and biochemistry to elucidate the self-assembly mechanism of a prokaryotic megacomplex called carboxysome. In addition to his work on carboxysomes, Dr. Chaijarasphong also has experiences in genetic engineering of microorganisms, protein engineering, and directed evolution of enzymes.

Prior to his PhDeducation, Dr. Chaijarasphong was a student in chemistry with focus on organic synthesis. He was awarded a DPST scholarship to study in the United States following his achievements in the International Chemistry Olympiad (IChO) competition in 2005 and 2006. For his bachelors degree, he attended Stanford University to study chemistry. During this time, he worked as an undergraduate researcher in the laboratory of Professor Barry Trost, where he assisted in optimizing the total asymmetric synthesis of bryostatin. He subsequently joined Professor Bianxiao Cuis group to assist in developing a fluorescent-based strategy for visualization of endosomal transport in rats cortical neurons.

Currently, Dr. Chaijarasphong is interested in applying his backgrounds in chemistry and biology to solving disease problems in shrimp, including genetically engineering shrimp for higher viral resistance and using biorthogonal chemistry to characterize shrimps cellular responses at the post-translational level.  




Last updated : 2/5/2017

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