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| Teacher ethics from Council of University Faculty Senate of Thailand |
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| Guidelines for Course Coordinator |
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Course Work : |
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Course Description for Undergrad |
| SCID 141 Living processes: From molecules to cell (3 credits) |
Schedule |
| Structures and functions of biomolecules, protein folding, protein functions, biocatalysis, enzyme kinetics, citric acid cycle, electron transport and oxidative phosphorylation, anabolism and catabolism of biomolecules in normal and some important pathological state, regulation of metabolic pathways, flow of genetic information, gene regulation, and molecular techniques with medical applications. |
Lecture 1, 2
Midterm Score
Grade (final) |
| SCID 142 Laboratory in living processes (1 credit) |
Schedule |
| Determination of LDH enzyme activity by spectrophotometric method, determination of aminotransferase activity in liver, DNA isolation and PCR amplification followed by analysis of DNA by gel electrophoresis technique. |
Laboratory Manual
Grade (final) |
| SCID 324 Medical Genetics (2 credit) |
Schedule |
| Fundamental concepts of genes, chromosomes, gene expression and their inheritance, features of human genome, organization, expression and regulation of genes on chromosomes, genetic variation, polymorphism and natural selection, types of selection and factors affecting human evolution including genetic mutations, mapping of human genome, molecular tools for analysis of genetic diseases, biochemical mechanism and molecular biology of genetic diseases of both single gene and multi-factorial disorders, carcinogenesis at the molecular level, treatment of genetic diseases, epidemiological study for prevention and therapy, genetic counseling and ethical conduct involving human research. |
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| SCBC 203
Basic Biochemistry (3 credits) |
Schedule |
| Structures and functions of four biomolecules, carbohydrate, lipid, protein and nucleic acid, metabolic processes and regulation of metabolic pathways of 4 biomolecules, flow of genetic information and gene regulation, DNA technology, role of biomolecules in normal physiological systems with some medical applications. |
Midterm |
| SCBC 204 Basic biochemistry laboratory (1 credit) |
Schedule |
| Basic biochemistry laboratory comprise 8 experiments involved in: preparation of acid-base solution and buffering system, using a basic instrument in analysis of biomolecules, determination a physical and chemical properties of all 4 biomolecules and study a metabolic process, that are related to the course Basic Biochemistry (SCBC 203) |
Midterm |
| SCBC 205 Physical principle in life science (2 credits) |
Schedule |
| Physical techniques in biological research, spectrophotometry, chromatography, electrophoresis and centrifugation, distribution and utilization of energy, laws of thermodynamics, chemical equilibrium, redox reactions, chemical and biochemical kinetics of catalytic reactions, properties of solutions, solubilization, micelle, colloid, pH, ionic strength and viscousity, physical properties of molecule, isomerism, symmetry, macromolecular structure and molecular bonding. |
Midterm score |
| SCBC 206 General biochemistry (3 credits) |
Schedule Summer |
| The study of structure and function of biomolecules that are carbohydrates, lipids, proteins and nucleic acids, controls and processes of metabolism at cellular levels promoted by specific catalysts, genes and gene expression from classical genetic to DNA technology and role of hormones and tissue functions relating in medical application. |
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Course Description for Postgrad - Compulsory Courses |
| SCBC 604 Biochemistry Seminar 1 (1 credit) |
Schedule |
| Seminar presentations by students, reading scientific papers, presentation of scientific papers, discussion, questions and answers of seminar presentation. |
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| SCBC 604 Biochemistry Seminar 2 (1 credit) |
Schedule |
| Seminar presentations by students, research progress, presentation of scientific progress, discussion, questions and answers of seminar presentation. |
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| SCBC 609 Structure and Mechanism of Enzymes (2 credit) |
Schedule |
| In-depth knowledge of structure and mechanism of selected groups of enzymes, physical principles and techniques used in studying structure and mechanism of proteins and enzymes, visualization of three dimensional structures of enzymes using the PyMOL program, current knowledge of mechanism underlying catalysis of hydrolase, protease, flavin-dependent enzymes, P450 enzymes, PLP-dependent enzyme, biotin-dependent enzyme, enzymes in drug design and biotechnology. |
Course Evaluation
Lecturer Evaluation |
| SCBC 610 Modern Metabolism (2 credit) |
Schedule |
| Various metabolic pathways, metabolisms of carbohydrate, lipid, amino acids and xenobiotics; regulation at the cellular and molecular levels including transcriptional, posttranscriptional and posttranslational regulations; dysregulations of certain metabolic pathways leading to the development of metabolic syndromes. |
Course Evaluation
Lecturer Evaluation |
| SCBC 611
Current Protocols in Biomolecular Research (1 credit) |
Schedule |
| Current techniques used in biochemical and biomolecular research, their applications in studying biomolecular functions; advantages, limitation and drawbacks of the techniques. |
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| SCBC 612
Functional Genetics and Genomics (2 credit) |
Course Webpage |
| Functional Genetics, Model Organisms, Genome Biology, Systems Biology, Comparative Genomics, and Evolutionary Genetics. |
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| SCID 502 Cell Science (2 credit) |
Schedule |
| Mechanism of cellular trafficking and processing among organelles; cellular communication; recognition, adhesion and interaction; cell cycle and controls of cellular differentiation and cancer; cellular signal transduction; reactions of cells to environmental stress factors and pathogens; cell injury, senescence, apoptosis and cell death; immune responses; molecular basis of some diseases. |
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| SCID 506 Concepts of Molecular Bioscience (2 credit) |
Schedule |
| Biochemical and biophysical knowledge underlying various processes of living systems, structures and functions of biological molecules, manipulation of energy and metabolites in biological systems, regulation and expression process of genetic materials. |
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| SCID 508 Biomolecular and Spectroscopy Techniques (1 credit) |
Schedule |
| Absorbance and fluorescence spectroscopy, mass spectroscopy, nuclear magnetic resonance (NMR) spectroscopy and biomolecular spectroscopy. |
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| SCID 509 Separation Techniques (1 credit) |
Schedule |
| Separation of biomolecules and biochemicals, based on size, shape, charge and state by using basic techniques such as centrifugation, chromatography, electrophoresis and dialysis. |
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| SCID 511 Gene Technology (1 credit) |
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| Gene manipulation and recombinant techniques, basic knowledge to understand the principles of gene technology; mini-projects involving handling of nucleic acids and proteins, evaluation of the quality of data generated. |
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| SCID 518 Generic Skills in Science Research (1 credit) |
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| Ethics for researchers; ethical consideration in the use of ideas, data and technology, human subjects and experimental animals; proper design and use of research protocols; methods in search for scientific information; techniques in formulating and writing research projects, i.e., thesis proposals and grant applications, research reports, theses and manuscripts for publication; intellectual property right; copyright versus plagiarism; proper credit acknowledgement. |
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Course Description for Postgrad - Elective Courses |
| GRID 612 Cell and Molecular Biology (3 credit) |
Schedule |
| Fundamental concepts of the bio-system with emphasis on the principles of biological structures, functions and their correlations at cellular and molecular levels. Topics of study cover six units i) the world of the cell, ii) cell structure and function, iii) energy flow in biosystem, iv) information flow in cells, v) cell division, cell differentiation, cell death and development, vi) evolution and biodiversity. |
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| GRID 617 Hypercourse on Bioinformatics (2 credit) |
Schedule |
| This course presents an overview of bioinformatics, bioinformatics for genome project, bioinformatic databases, application software from public domains evolution computation, supercomputers and parallel process in biology, molecular modeling |
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| GRID 618 Cybertools for Research (1 credit) |
Schedule |
| This web-based course covers the use of various cybertools for research such as digital library, web technology and statistical package. Contents of cybertools for research : research planning, execution and management, search for information resources from digital libraries/Internet, using the online databases (deep web, invisible web), acquiring the articles from e-journals, inter-library loan, Thai databases, technical writing in e- environment, how to write electronics documents (xml), how to construct webpage, statistics for research, data from survey and experimental design, use of statistical packages, case study, how to choose proper statistics for your research. |
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| SCBC 601 Physical Biochemistry (2 credit) |
Schedule |
| A broad foundation of physico-chemical principles and structural concepts that are relevant and directly applicable to the field of molecular bioscience, visualizing the cellular, subcellular and biomolecular worlds in three dimensions, and understanding the physical and chemical parameters involved in biological system. |
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| SCBC 603 Advanced Biochemistry Laboratory (2 credit) |
Schedule |
| A short research project, laboratory techniques related to biochemical research, introduction to research methodologies used in biochemical research. |
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| SCBC 607 Current Topics in Biochemistry (3 credit) |
Schedule |
| Up-to-date information in various areas of biochemistry; selected topics of current interest and of potential research importance for Thailand; reading research articles and presentation in the form of a seminar. |
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| SCBT 502 Recombinant DNA Technology (3 credit) |
Schedule |
| The course covers the principles and techniques used in recombinant DNA technology. Topics will include DNA structure and function, and regulation of gene expression in various systems ranging from bacteria, yeast, fungi, plants and animals. Lectures will emphasize recombinant DNA techniques (molecular cloning, restriction enzyme mapping, expression of cloned genes, library construction) and other ;techniques for genetic analysis. Knowledge on classical bacterial genetics (transformation, conjugation and transduction and strain manipulation), bacterial physiology, together with knowledge and skills to carry out research in the field will be provided to the students. |
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| SCBT 602 Gene Regulation (3 credit) |
Schedule |
| Structure of gene either a single gene, operon or gene cluster in organisms, regulation of gene expression in various systems, viruses, bacteria, fungi and yeasts, animal and human cell culture, insects, as well as plant, cascade in gene regulation from chromosome to transcription, splicing (in eukaryote), modifications, protein synthesis and protein turnover, role of gene in differentiation, development, pathogenicity as well as some bioactive compound biosynthesis. |
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| SCID 503 Systemic Bioscience (3 credit) |
Schedule |
| Structure of tissues, organs, and organ systems of the body; the functional roles and the regulation of various organ systems; role of organ systems in the body homeostasis in face of environmental change and disease; frontier knowledge in systemic bioscience research. |
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| SCID 507 Microscopic Technique (1 credit) |
Schedule |
| Structure and operation of light microscope transmission electron microscope (TEM), scanning electron microscope (SEM), confocal microscope and fluorescence microscope; specimen collection, fixation, sectioning, basic staining and immunocytochemical methods for microscopy; examination, photography and interpretation of the results. |
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| SCID 510 Immunological Methods (1 credit) |
Schedule |
| The importance of immunology and immunological methods; antigen, immunogen, epitope, hapten, adjuvant; antigen-antibody interaction and immunological specificity, immunological reagents, principle of immunological laboratory tests and quality assurance. |
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