Pornpimol Rongnoparut

Associate Professor Dr.
Ph.D. (University of Illinois at Chicago), USA
Tel : +662-201-5453
Fax :+662-354-7174
Email : pornpimol.ron@mahidol.ac.th
 
Research Interests :
Molecular biology and functional studies of the cytochrome P450 genes that play role in detoxification of xenobiotics in insects and of the P450 gene in the bile acid synthesis pathway
 
Current Research :
My main interest in research has recently been focused on the role of Anopheles minimus CYP6AA3 and CYP6P7 cytochrome P450 enzymes in the metabolism of pyrethroid insecticides. The specific aims are to:
1) Establish the CYP6AA3 and CYP6P7 cytochrome P450s and the the NADPH-cytochrome P450 reductase (CPR) expression system.
2) Express CYP6AA3 and CYP6P7 enzymes and examine the substrate preferences of the enzymes relative to pesticide metabolism, using cytochrome P450-CPR reconstitution system.
3) Mutation of CPR and activity studies