Academic Staff


Boonsirm Withyachumnarnkul

Centex Shrimp, Room K436
Faculty of Science, Mahidol University
Bangkok, 10400, Thailand

Telephone: (+66) (0)2201 5866
Fax: (+66) (0)2354 7168



Research Interest

The black tiger shrimp, Penaeus monodon, is the large-sized shrimp commercially cultivated in many countries in Asia.  Several problems concerning cultivation of this species, especially disease outbreaks and the industry still requires the production of domesticated stocks. My main interest is on domestication and selective breeding of this shrimp species.  These include disease screening by DNA-based technologies, such as by polymerase chain reaction methods and by in situ hybridization.  Selective breeding program requires genetic studies, with on-field research and production of specific pathogen-free stocks.

We are in a researcher group called Center of Excellence for Shrimp Molecular Biology and Biotechnology or Centex Shrimp, which is composed of more than 50 researchers working to solve shrimp problems.  Besides the domestication and selective breeding program, my research activities are directed by problems posing on shrimp industry as well.  Most of the problems are disease outbreaks, such as white-spot disease, yellow-head disease, etc.  In-depth research in the mechanisms of virus-shrimp cell interactions in thus one of our major activities.  Our interest are therefore to find ways to solve problems in the field, as well as to perform basic researches aiming at discovering mysterious mechanisms of the infectious process in shrimp.

Honors & Awards

1989 - 1992     King Anantamahidol Award
1996               Best Scientist Award: From Charoen Pokphand Foods Company Limited
1997               Golden Shrimp Award: From Shrimp Farmer Association of Suratthanee
1997               Inventer Award From the National Research Council
2001               Toray Science Foundation Award
2003               Best Biotechnology Award

Selected Publications

Kruevaisayawan H, Vanichviriyakit R, Weerachatyanukul W, Withyachumnarnkul B, Basak A, Tanphaichitr A, Sobhon P (2007) Binding Components in Egg Water and Sperm Derived Trypsin Regulate Sperm Acrosome Reaction in Black Tiger Shrimp, Penaeus monodon. Aquaculture (in press).

Poltana P, Lerkitkul T, Pongtippatee-Taweepreda P, Asuvapongpattana, S, Wongprasert K, Sriurairatana S, Chavadej J, Sobhon P, Olive PJW, Withyachumnarnkul B (2007) Culture and devlopment of the polychaete Perinereis cf nuntia. Inv Reprod Devel (in press).

Wongprasert K, Asuvapongpatana S, Poltana, P, Tiensuwan M, Withyachumnarnkul B (2006) Serotonin stimulates ovarian maturation and spawning in the black tiger shrimp Penaeus monodon. Aquaculture 261, 1447-1454.

Meeratana, P, Withyachamnarnkul, B, Damrongphol, P, Wongprasert, K, Suseangtham, A., Sobhon, P (2006) Serotonin induces ovarian maturation in giant freshwater prawn broodstock, Macrobrachium rosenbergii de Man. Aquaculture 260, 315-325.

Zhipeng L, Sobhon P, Withyachumnarnkul B, Hanna P (2006) Identification of a putative egg-laying hormone in neural and ovarian tissues of the black tiger shrimp, Penaeus monodon, using immunocytochemistry. Invert Neurosci 6(2), 41-46.

Sritunyalucksana K, Apisawetakan S, Boon-nat A, Withyachumanrnkul B, Flegel T (2006) A new RNA virus found in black tiger shrimp Penaeus monodon from Thailand. Virus Res 118, 31-38.

Anantasomboon G, Sriurairatana S, Flegel TW and Withyachumnarnkul B (2006) Unique lesions and virus-like particles found in growth retarded black tiger shrimp Penaeus monodon from East Africa. Aquaculture 253: 197-203.

Withyachumnarnkul B, Chayaburakul K, Lao-Aroon S, Plodpai P, Sritunyalucksana K and Nash G (2006) Normal growth and reproductive performance by Penaeus monodon infected with infectious hypodermal and hematopoietic necrosis virus (IHHNV). Dis Aquat Org 69:129-136.

Chayaburakul K, Lightner DV, Sriurairattana S, Nelson KT and Withyachumnarnkul B (2006) Different responses to infectious hypodermal and hematopoietic necrosis virus (IHHNV) in Penaeus monodon and Penaeus vannamei. Dis Aquat Org 67:191-200.

Laoaroon S, Boonnat A, Poltana P, Kanchanaphum P, Gangnonngiw W, Nash G and Withyachumnarnkul, B (2005) Infectivity of white-spot syndrome virus (WSSV) to the polychaete Pereneis nuntia and a possibility of WSSV transmission from the polychaete to the black tiger shrimp Penaeus monodon. In P. Walker, R. Lester and M.G. Bondad-Reantaso (eds). Diseases in Asian Aquaculture V, pp 353-361. Fish Health section, Asian Fisheries Society, Manila.

Attaphon Satidkanitkul A, Sithigorngul P, Sang-oum W, Rukpratanporn S, Sruurairatana S, Withyachumnarnkul B and Flegel T (2005) Synthetic peptide used to develop antibodies for detection of polyhydrin from monodon baculovirus (MBV) Dis Aquat Org 65:79-84.

Somapa KS, Wongprasert K, Khanobdee K, Meeratana P, Pongtippatee TP and Withyachumnarnkul B (2004) Vibrio bacterin and carboxymethyl -1,3-glucans protect Penaeus monodon from Vibrio harveyi infection. J Aquatr Animal Hlth 16:238-245.

Chayaburakul K, Nash G, Pratanpipat P, Sriurairatana S, Withyachumnarnkul B (2004) Multiple pathogens found in growth-retarded black tiger shrimp Penaeus monodon cultivated in Thailand. Dis Aquat Org 60:89-96.

Vanichviriyakit R, Kruevaisayawan H, Weerachatyanukul W, Pongtippatee-Tawipreeda P, Withyachumnarnkul B, Pratoomchat B, Chavadej J, Sobhon P (2004) Molecular modification of Penaeus monodon sperm in female thelycum and its consequent responses. Mol Reprod Devel 69: 356-363.

Pongtippatee-Taweepreda P, Chavadej J, Plodpai P, Pratoomchart B, Sobhon P, Weerachatyanukul W and Withyachumnarnkul B (2004) Egg Activation in the Black Tiger Shrimp Penaeus monodon. Aquaculture 234: 183-198.

Wongprasert K, Khanobdee K, Somapa-Glannukarn S, Meeratana P, and Withyachumnarnkul B (2003) Time-course and levels of  apoptosis in various tissues of the black tiger shrimp Penaeus monodon infected with white spot syndrome virus. Dis Aquat Org 55: 3-10.

Wongteerasupaya C, Pungchai P, Withyachumnarnkul B, Boonsaeng V, Panyim S, Flegel TW, and Walker P (2003) High variation in repetitive DNA fragment length for white spot syndrome virus (WSSV) isolates in Thailand. Dis Aquat Org, 54, 253-257.

Withyachumnarnkul B, Boonsaeng V, Chomsoong R, Flegel TW, Muangsin S and Nash GL (2003) Seasonal variation in white spot syndrome virus-positive samples in broodstock and post-larvae of Penaeus monodon in Thailand. Dis Aquat Org 53: 167-171.

Sukhumsirichart W, Kiatpathomchai W, Wongteerasupaya C, Withyachumnarnkul B, Flegel TW, Boonsaeng V and Panyim S (2002) Detection of hepatopancreatic parvovirus (HPV) infection in Penaeus monodon using PCR-ELISA. Mol Cell Probes 16: 409-413.

Phromjai J, Boonsaeng V, Withyachumnarnkul B, Flegel TW (2002) Detection of hepatopancreatic parvovirus in Thai shrimp Penaeus monodon by in situ hybridization, dot blot hybridization and PCR amplification. Dis Aquat Org 51: 227-232.

Nuntakarn L, Mevatee U, Withyachumnarnkul B, Leardkamolkarn V and Fuchareon S (2002) Application of micro-FISH for characterization of structural human chromosome abnormalities. SienceAsia 28: 1-9.

Khanobdee K, Soowannayan C, Flegel TW, Ubol S and Withyachumnarnkul B (2002) Evidence for apoptosis correlated with mortality in the giant black tiger shrimp Penaeus monodon infected with yellow head virus. Dis Aquat Org 48(2): 79-90.






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Last update : Wednesday, 21 January 2009