| Education:
|
| 1992 |
B.Sc. (First Class
Hons) Chemistry, Prince of Songkla
University,Thailand |
| 1997 |
Ph. D. Biological Chemistry,
University of Michigan, Ann Arbor,
U.S.A. |
|
|
| Research
and Professional Experiences:
|
| 1993, 1996 |
Teaching assistant in Biochemistry
Laboratory (BC 416/516) for undergraduate
students and graduate students,
University of Michigan, Ann Arbor. |
| 1994 |
Teaching assistant in Enzyme
Kinetics (BC 573) for graduate
students, University of Michigan,
Ann Arbor. |
| 1997-2001 |
Lecturer, Department of Biochemistry,
Faculty of Science, Mahidol University |
| 2001-2005 |
Assistant Professor, Department
of Biochemistry, Faculty of Science,
Mahidol University |
| 2005-2009 |
Associate Professor, Department
of Biochemistry, Faculty of Science,
Mahidol University |
| 2008-2009 |
Deputy Chair, Department of
Biochemistry, Faculty of Science,
Mahidol University |
| 2009-2011 |
Chair, Department of Biochemistry,
Faculty of Science, Mahidol University |
| 2009-present |
Professor, Department
of Biochemistry, Faculty of Science,
Mahidol University |
| 2011-present |
Deputy Dean for Research, Faculty of Science, Mahidol University |
|
|
| Awards
and Distinctions : |
| 1985 |
Recipient of Distinguished Student
Award from Princess Sirindhorn |
| 1985-1997 |
Recipient of Scholarship from
Development and Promotion of Science
and Technology Talent Project |
| 1993 |
Recipient of Dr.Tap Nilaniti
Outstanding Graduate Award |
| 1995 |
Recipient of Chrisman Award
from Department of Biological
Chemistry, University of Michigan,
Ann Arbor. (for outstanding Ph.D.
candidate) |
| 1998 |
Recipient of Murphy Award from
Department of Biological Chemistry,
University of Michigan, Ann Arbor.
(for the outstanding publication
series) |
| 2000 |
Recipient of Federation of Asian
and Oceanic Biochemistry and Molecular
Biology (FAOBMB) travel fellowship |
| 2003 |
Recipient of the L'oreal-Unesco
Fellowship for Woman in Science
in Thailand |
| 2005 |
Young Scientist Award, Foundation
for the Promotion of Science and
Technology under the Patronage
of H. M. the King, Thailand. |
| 2008 |
Affiliate Fellow of TWAS (The
Academy of Sciences for the Developing
World) |
| 2009 |
BMB Award from Section of Biochemistry
and Molecular Biology, The Science
Society of Thailand under the
Patronage of His Majesty the King. |
| 2009 |
Faculty of Science Outstanding
Lecturer Award (First-Middle Level) |
| 2010 |
Exemplary Lecturer Award from
Mahidol University Faculty Senate |
| 2010 |
Taguchi Prize for Outstanding
Research Achievement in Biotechnology |
| 2010 |
TRF-CHE-Scopus Researcher Award
2010 |
| 2011 |
Outstanding Alumni Award 2011 from Prince of Songkla University  |
|
|
| Ad
Hoc Journal Reviewer :
|
| |
Acta
Crystallographica Section F |
| |
Applied
Microbiology and Biotechnology |
| |
Archives
of Biochemistry and Biophysics |
| |
Advanced Synthesis & Catalysis |
| |
Biochemistry |
| |
Biochimica
Biophysica Acta |
| |
Bioresource
Technology |
| |
Chemistry & Biology |
| |
FEMS Microbiology Letter |
| |
Journal of Agricultural and Food Chemistry |
| |
Journal
of Chemical Education |
| |
Journal of the American Chemical Society |
| |
The Journal of Biological Chemistry (JBC) |
| |
|
| Reviewer
of Funding Organizations :
|
| |
Austrian
Science Fund |
| |
National Science Foundation (NSF, USA.) |
| |
The
Thailand Research Fund (TRF) |
| |
National
Science and Technology Development
Agency (NSTDA) |
| |
Commission
on Higher Education (CHE),
Ministry of Education |
| |
Mahidol
University |
| |
|
| Field
of Interest : |
| |
Enzymology; Enzymes
Enzyme catalysis; Enzyme mechanism
Flavin and Flavoproteins
Enzyme Kinetics; Pre-steady state
kinetics
Redox Enzymes; pyridoxal-5-phosphate
Physical Biochemistry; Biosensor
|
|
|
| Publications
: |
| Journal
Articles |
| 1997 |
| 1. |
Chaiyen
P, Brissette P, Ballou
DP, Massey V. Reaction of 2-methyl-3-hydroxypyridine-5-carboxylic
acid (MHPC) oxygenase with N-methyl-5-hydroxynicotinic
acid: Studies on the mode of binding,
and protonation status of the
substrate. Biochemistry
1997;36(45):13856-64. |
| |
|
| 2. |
Chaiyen
P, Ballou DP, Massey
V. Gene cloning, sequence analysis,
and expression of 2-methyl-3-hydroxypyridine-5-carboxylic
acid oxygenase. Proceedings
of the National Academy of Sciences
of the United States of America
1997;94(14):7233-8. |
| |
|
| 3. |
Chaiyen
P, Brissette P, Ballou
DP, Massey V. Unusual mechanism
of oxygen atom transfer and product
rearrangement in the catalytic
reaction of 2-methyl-3-hydroxypyridine-5-carboxylic
acid oxygenase. Biochemistry
1997;36(26):8060-70. |
| |
|
| 4. |
Chaiyen
P, Brissette P, Ballou
DP, Massey V. Thermodynamics and
reduction kinetics properties
of 2-methyl-3- hydroxypyridine-5-carboxylic
acid oxygenase.
Biochemistry 1997;36(9):2612-21.
|
| |
|
| 2001 |
| 5. |
Chaiyen
P, Suadee C, Wilairat
P. A novel two-protein component
flavoprotein hydroxylase p-hydroxyphenylacetate
hydroxylase from Acinetobacter
baumannii. European
Journal of Biochemistry 2001;268(21):5550-61. |
| |
|
| 2004 |
| 6. |
Chaiyen
P, Sucharitakul J, Svasti
J, Entsch B, Massey V, Ballou
DP. Use of 8-Substituted-FAD Analogues
to Investigate the Hydroxylation
Mechanism of the Flavoprotein
2-Methyl-3-hydroxypyridine-5-carboxylic
Acid Oxygenase. Biochemistry
2004;43(13):3933-43. |
| |
|
| 7. |
Thotsaporn
K, Sucharitakul J, Wongratana
J, Suadee C, Chaiyen P.
Cloning and expression of p-hydroxyphenylacetate
3-hydroxylase from Acinetobacter
baumannii: Evidence of the
divergence of enzymes in the class
of two-protein component aromatic
hydroxylases. Biochimica
et Biophysica Acta - Gene Structure
and Expression 2004;1680(1):60-6. |
| |
|
| 2005 |
| 8. |
Hommalai
G, Chaiyen P,
Svasti J. Studies on the transglucosylation
reactions of cassava and Thai
rosewood b-glucosidases
using 2-deoxy-2-fluoro-glycosyl-enzyme
intermediates. Archives
of Biochemistry and Biophysics
2005;442(1):11-20. |
| |
|
| 9. |
Oonanant
W, Sucharitakul J, Yuvaniyama
J, Chaiyen P.
Crystallization and preliminary
X-ray crystallographic analysis
of 2-methyl-3-hydroxypyridine-5-carboxylic
acid (MHPC) oxygenase from Pseudomonas
sp. MA-1. Acta
Crystallographica Section F: Structural
Biology and Crystallization Communications
2005;61(3):312-4. |
| |
|
| 10. |
Sucharitakul
J, Chaiyen P,
Entsch B, Ballou DP. The reductase
of p-hydroxyphenylacetate 3-hydroxylase
from Acinetobacter baumannii
requires p-hydroxyphenylacetate
for effective catalysis. Biochemistry
2005;44(30):10434-42. |
| |
|
| 2006 |
| 11. |
Kujawa
M, Ebner H, Leitner C, Hallberg
BM, Prongjit M, Sucharitakul J,
Ludwig R, Rudsander U, Peterbauer
C, Chaiyen P,
Haltrich D, Divne C. Structural
basis for substrate binding and
regioselective oxidation of monosaccharides
at C3 by pyranose 2-oxidase. Journal
of Biological Chemistry 2006;281(46):35104-15. |
| |
|
| 12. |
Sucharitakul
J, Chaiyen P,
Entsch B, Ballou DP. Kinetic mechanisms
of the oxygenase from a two-component
enzyme, p-hydroxyphenylacetate
3-hydroxylase from Acinetobacter
baumannii. Journal
of Biological Chemistry 2006;281(25):17044-53. |
| |
|
| 2007 |
| 13. |
Alfieri
A, Fersini F, Ruangchan N, Prongjit
M, Chaiyen P,
Mattevi A. Structure of the monooxygenase
component of a two-component flavoprotein
monooxygenase. Proceedings
of the National Academy of Sciences
of the United States of America
2007;104(4):1177-82. |
| |
|
| 14. |
Suadee
C, Nijvipakul S, Svasti J, Entsch
B, Ballou DP, Chaiyen
P. Luciferase from Vibrio
campbellii is more thermostable
and binds reduced FMN better than
its homologues. Journal
of Biochemistry 2007;142(4):539-52. |
| |
|
| 15. |
Sucharitakul
J, Phongsak T, Entsch B, Svasti
J, Chaiyen P,
Ballou DP. Kinetics of a two-component
p-hydroxyphenylacetate
hydroxylase explain how reduced
flavin is transferred from the
reductase to the oxygenase. Biochemistry
2007;46(29):8611-23. |
| |
|
| 2008 |
| 16. |
Nijvipakul
S, Wongratana J, Suadee C, Entsch
B, Ballou DP, Chaiyen
P. LuxG is a functioning
flavin reductase for bacterial
luminescence. Journal
of Bacteriology 2008;190(5):1531-8. |
| |
|
| 17. |
Sucharitakul
J, Prongjit M, Haltrich D, Chaiyen
P. Detection of a C4a-Hydroperoxyflavin
Intermediate in the Reaction of
a Flavoprotein Oxidase.
Biochemistry 2008;47(33):8485–90.
|
| |
|
| 2009 |
| 18. |
Spadiut
O, Pisanelli I, Maischberger T,
Peterbauer C, Gorton L, Chaiyen
P, Haltrich D. Engineering
of pyyranose 2-oxidase: improvement
for biofuel cell and food applications
through semi-rational protein
design. Journal
of Biotechnology 2009;
139(3):250-7. |
| |
|
| 19. |
Prongjit M, Sucharitakul
J, Wongnate T, Haltrich D, Chaiyen
P. Kinetic mechanism
of pyranose 2-oxidase from Trametes
multicolor.
Biochemistry 2009;48(19):4170-80.
|
| |
|
| 20. |
Chosrowjan H, Taniguchi
S, Mataga N, Phongsak T, Sucharitakul
J, Chaiyen P,
Tanaka F. Ultrafast Solvation
Dynamics of flavin mononucleotide
in the reductase component of
p-Hydroxyphenylacetate Hydroxylase.
Journal
of Physical Chemistry B 2009;113(25):8439-42. |
| |
|
| 21. |
Baron R, Riley
C, Chenprakhon P, Thotsaporn K,
Winter RT, Alfieri A, Forneris
F, van Berkel WJH, Chaiyen
P, Fraaije MW, Mattevi
A, McCammon JA. Multiple pathways
guide oxygen diffusion into flavoenzyme
active sites. Proceedings
of the National Academy of Sciences
of the United States of America
2009;106(25):10603-8. |
| |
[ Cited in
"Research Highlights"
Nature Chemistry, 2009] |
| |
|
| 22. |
Sopitthammakhun
K, Maenpuen S, Yuthavong Y, Leartsakulpanich
U, Chaiyen P.
Serine hydroxymethyltransferase
from Plasmodium vivax is different
in substrate specificity from
its homologues. FEBS
Journal 2009;276(15):4023-36.
|
| |
|
| 23. |
Maenpuen S, Sopitthammakhun
K, Yuthavong Y, Chaiyen
P, Leartsakulpanich U.
Characterization of Plasmodium
falciparum serine hydroxymethyltransferase—A
potential antimalarial target.
Molecular
and Biochemical Parasitology 2009;168(1):63-73.
|
| |
|
| 2010 |
| 24. |
Chaiyen
P. Flavoenzymes
catalyzing oxidative aromatic
ring-cleavage reactions. Arch
Biochem Biophys. 2010;493(1):62-70.
(Review) |
| |
|
| 25. |
Pitsawong W, Sucharitakul
J, Prongjit M, Tan TC, Spadiut
O, Haltrich D, Divne C, Chaiyen
P. A conserved active-site
threonine is important for both
sugar and flavin oxidations of
pyranose 2-oxidase. Journal
of Biological Chemistry 2010;285(13):9697-705. |
| |
|
| 26. |
Sucharitakul J,
Wongnate T, Chaiyen P.
Kinetic isotope effects on the
noncovalent flavin mutant protein
of pyranose 2-oxidase reveal insights
into the flavin reduction mechanism.
Biochemistry 2010;49(17):3753-65.
|
| |
|
| 27. |
Chenprakhon P,
Sucharitakul J, Panijpan B,
Chaiyen P. Measuring
binding affinity of protein. Ligand
interaction using spectrophotometry:
binding of neutral red to riboflavin-binding
protein. Journal
Chemical Education 2010;87(8):829-31. |
| |
|
| 28. |
Rujkorakarn R,
Nunthaboot N, Tanaka F,
Chaiyen P, Chosrowjan
H, Taniguchi S, Mataga N. Time-resolved
Stokes shift in proteins with
continuum model: Slow dynamics
in proteins.
Journal of Photochemistry and
Photobiology A: Chemistry 2010;215(1):38-45. |
| |
|
| 29. |
Tan TC, Pitsawong
W, WongnateT, Spadiut O, Haltrich
D, Chaiyen P,
Divne C. H-bonding and Positive
Charge at the N(5)/O(4) Locus
are Critical for Covalent Flavin
Attachment in Trametes Pyranose
2-Oxidase.
Journal of Molecular Biology 2010;402(3):578-94
|
| |
|
| 30. |
Nijvipakul S, Ballou
SP, Chaiyen P.
Reduction Kinetics of a Flavin
Oxidoreductase LuxG from Photobacterium
leiognathi (TH1):Half Sites Reactivity.
Biochemistry 2010;49 (43):9241–8
|
| |
|
| 2011 |
| 31. |
Ruangchan N, Tongsook
C, Sucharitakul J, Chaiyen
P. pH-dependent studies
reveal an efficient hydroxylation
mechanism of the oxygenase component
of p-hydroxyphenylacetate 3-hydroxylase.
Journal
of Biological Chemistry 2011;286(1):223-33. |
| |
|
| 32. |
Sucharitakul J,
Wongnate T, Chaiyen P. Hydrogen peroxide elimination
from C4A-hydroperoxy-flavin in
a flavoprotein oxidase occurs
through a single proton transfer
from flavin N5 to a peroxide leaving
group. Journal
of Biological Chemistry 2011;286(19):16900-9. |
| |
|
| 33. |
Thotsaporn K, Chenprakhon P, Sucharitakul J, Mattevi A, Chaiyen P. Stabilization of C4A-hydroperoxy-flavin in a two-component flavin-dependent monooxygenase is achieved through interactions at flavin N5 and C4a atoms. Journal
of Biological Chemistry 2011;286(32):28170-80. |
| |
|
| 34. |
Penpassakarn P, Chaiyen P, Palittapongarnpim P. Efficient heterologous expression and one-step purification of fully active c-terminal histidine-tagged uridine monophosphate kinase from Mycobacterium tuberculosis. The Southeast Asian Journal of Tropical Medicine and Public Health 2011;42(6):1452-1459. |
| |
|
| 35. |
Wongnate T, Sucharitakul J , and Chaiyen P. Identification of a catalytic base for sugar oxidation in pyranose 2-oxidase reaction. Chembiochem 2011;12(17):2577-86. |
| |
|
| 36. |
Tongsook C, Sucharitakul J, Thotsaporn K, Chaiyen P. Interactions with the substrate phenolic group are essential for hydroxylation by the oxygenase component of p-hydroxyphenylacetate 3-hydroxylase. Journal of Biological Chemistry 2011;286(52):44491–502. |
| |
|
| 2012 |
| |
|
| 37. |
Chenprakhon P, Panijpan B, Chaiyen P. An Experiment Illustrating the Change in Ligand pKa upon Protein Binding. Journal of Chemical Education 2012, in press.  |
| |
|
| 38. |
Chosrowjan H, Taniguchi S, Wongnate T, Sucharitakul J, Chaiyen P, Tanaka F. Conformational heterogeneity in pyranose 2-oxidase from Trametes multicolor revealed by ultrafast fluorescence dynamics. Journal of Photochemistry and Photobiology A: Chemistry 2012;234(April 15):44-48.  |
| |
|
| 39. |
Oonnanat W, Sucharitakul J, Chaiyen P, Yuaniyama J. Crystallization and preliminary X-ray analysis of the reductase component of p-hydroxyphenylacetate 3-hydroxylase from Acinetobacter baumannii. Acta Crystallographica Section F 2012, in press.  |
| |
|
| 40. |
Sucharitakul J, Wongnate T, Montersino S, van Berkel, WJH, Chaiyen P. Reduction Kinetics of 3-Hydroxybenzoate 6-Hydroxylase from Rhodococcus jostii RHA1. Biochemistry 2012. Just Accepted.  |
| |
|
| 41. |
Somprasong N, Jittawuttipoka T, Duang-nkern J, Romsang, A, Chaiyen P, Schweizer H, Vattanaviboon P, Mongkolsuk S. Pseudomonas aeruginosa thiol peroxidase protects against hydrogen peroxide toxicity and displays atypical patterns of gene regulation. Journal of Bacteriology 2012. Just Accepted.  |
|
|
| Chapter
in Book (Annual Report) |
1. |
Chaiyen P,
Suadee C, Meevoothisom V. Degradation
of phenylacetic acid by bacteria
from Thai soil. In: Annual Report
of ICBiotech. Vol. 21. Osaka:
International Center for Biotechnology;
1998. p. 862-7. |
|
|
| Papers
in Proceedings |
1. |
Chaiyen P,
Suadee C, Thotsaporn K, Svasti
J. Studies
of the two-component p-hydroxyphenylacetate
hydroxylase from Acinetobacter
baumannii. In: Chapman
S, Perham R, Scrutton N, editors.
Flavins and Flavoproteins 2002:
Proceedings of the Fourteenth
International Symposium; 2002
July 14-18; St. John's College,
University of Cambridge, Uk.
Berlin: Agency for Scientific
Publications; 2002. p. 975-80.
|
2. |
Sucharitakul J, Chaiyen
P, Ballou DP, Massey
V. Probing
the mechanism of 2-methyl-3-hydroxypyridine-5-carboxylic
acid oxygenase by using 8-substituted-FAD
analogs. In: Chapman S,
Perham R, Scrutton N, editors.
Flavins and Flavoproteins 2002:
Proceedings of the Fourteenth
International Symposium; 2002
July 14-18; St. John's College,
University of Cambridge, Uk.
Berlin: Agency for Scientific
Publications; 2002. p. 381-6.
|
3. |
Sucharitakul J, Chaiyen
P, Entsch B, Ballou
DP. Mechanistic
studies on the reductase component
of p-hydroxyphenylacetate
3-hydroxylase from Acinetobacter
baumannii.. In: Nishino
T, Miura R, Tanokura M, Fukui
K, editors. Flavins and Flavoproteins
2005: Proceedings of the Fifteenth
International Symposium; 2005
April 17-22; Shonan Village
Center, Hayama, Japan: ARchiTect
Inc.; 2005. p. 275-80.
|
4. |
Chaiyen P,
Phongsak T, Sucharitakul J,
Ballou DP. Review
and perspectives of how reduced
flavin is transferred between
the reductase and oxygenase
p-hydroxyphenylacetate 3-hydroxylase.
In: Frago S, Gomez-moreno C,
Medina M, editors. Flavins and
Flavoproteins 2008: Proceedings
of the Sixteenth International
Symposium; 2008 June 8-13; Jaca,
Spain: Prensas Universitarias
de Zaragoza; 2008. p. 27-44. |
|
|
| Oral
Presentations (International Level) |
1. |
Oral Presentation
“p-Hydroxyphenylacetic
acid hydroxylase from Acinetobacter
baumannii” 15th the Federation
of Asian and Oceanian Biochemists
and Molecular Biologists (FAOBMB)
Symposium, Beijing, China, October
21-24, 2001. |
| |
|
2. |
Invited Seminar Lecture
"Reduced Flavin Transfer
between Components of p-Hydroxyphenyl-
acetate 3-Hydroxylase". A
seminar at University of Pavia,
Italy, June 12, 2006. |
| |
|
3. |
Invited Symposium Lecture
"How the reductase and oxygenase
work together in a two-component
flavoenzyme, p-hydroxyphenylacetate".
16th
International Symposium on Flavins
and Flavoproteins, Jaca, Spain
, Jun 10, 2008. |
| |
|
| 4. |
Invited
Speaker
Gordon Research Conference 2010:
Enzymes, Co-enzymes & Metabolic
Pathways "What is necessary
for C4a-hydroperoxy-FAD formation
in pyranose 2-oxidase reacion?"
July 19-23, 2010 at Waterville
Valley Resort, New Hampshire,
USA. |
| |
|
| 5. |
Invited seminar lecture
" Exploring the Reaction
Mechanism of Pyranose 2-Oxidase
Through Transient Kinetics and
Site-Directed Mutagenesis"
at Wake Forest University, July
27, 2010, Winston-Salem, North
Carolina, USA. |
| |
|
| 6. |
Invited Symposium lecture
“Oxygenation mechanism of p-hydroxyphenylacetate hydroxylase, a two-component flavin-dependent monooxygenase”. The 3rd Asia Pacific Protein Association (APPA) Conference, May 6-9, Shanghai, China. |
| |
|
| 7. |
Invited Symposium lecture
“Use of Kinetic Isotope Effects and Transient Kinetics to Unravel the Mechanism of H2O2 Elimination from C4a-Hydroperoxy-flavin in Pyranose2-Oxidase”. The IXth European Symposium of The Protein Society. May 22-26, 2011, Stockholm, Sweden. |
| |
|
| 8. |
Invited Symposium lecture
“Understanding reaction mechanisms of two-component flavin-dependent monooxygenases through a model of p-hydroxyphenylacetate hydroxylase”. 17th International Conference on Cytochrome P450, at The University of Manchester, UK 26th to 30th of June, 2011. |
| |
|
| |
|
| 9. |
Oral Presentation
Mechanistic Studies of Flavin- and PLP-Dependent Enzymes. Presentation by TWAS young affiliate at 22nd General Meeting at International centre in Theroretical Physics, Trieste, Italy, on 21-23 November 2011. |
| |
|
|
|
| Invited Symposium Lectures in Thailand |
1. |
Chaiyen P,
Sucharitakul J, Thotsaporn K,
Suadee C, Entsch B, Ballou DP.
2005. Two-component flavoproteins
in oxygenation reactions. The
2nd Protein Research Network Symposium
on Proteins Structure, Function,
and Proteomics, Chulabhorn Research
Institute Conference Center, Bangkok,
Thailand. |
| |
|
2. |
Chaiyen C,
Sucharitakul J, Suadee C, Thotsaporn
K, Entsch B, Ballou DP. 2005.
Reaction Mechanism of p-Hydroxyphenylacetate
Hydroxylase. The 31th Congress
on Science and Technology of Thailand,
Nakhon Ratchasima, Thailand. |
| |
|
3. |
Chaiyen P,
Nijvipakul S, Suadee C. 2006.
A Novel Luciferase From Vibrio
Cambellii : Implication on residues
important for reduced FMN binding.
Annual Conference of Thai Society
for Biotechnology, Bangkok, Thailand. |
| |
|
4. |
Chaiyen P,
Sucharitakul J, Phongsak T, Entsch
B, Ballou DP. 2006. Reduced Flavin
Transfer between components of
p-hydroxyphenylacetate hydroxylase.
First Annual Symposium of the
Protein Society of Thailand, October
24-25, Bangkok, Thailand. |
| |
|
5. |
Chaiyen
P. 2009. Use of Pre-Steady
State Kinetics to Elucidate Reaction
Mechanisms of Flavin-Dependent
Enzymes. The 2nd Biochemistry
and Molecular Biology (BMB) Conference
2009: Biochemistry and Molecular
Biology for Regional-Sustainable
Development, May 7-8, 2009, Khonkaen. |
| |
|
6. |
Chaiyen
P. 2009. Plasmodium serine
hydroxymethyl transferase as an
antimalarial target. Fourth Annual
Symposium Protein Society of Thailand
Protein Research: from Basic Studies
to Applications in Health Sciences,
Aug 21, 2009, Chulabhorn Research
Institute, Bangkok, Thailand. |
| |
|
7. |
Chaiyen
P. 2010. Pyranose 2-Oxidase:
Kinetics and Mechanisms. PACCON
2010 Pure and Applied Chemistry
Conference 2010, Jan 21-23, 2010,
Sunee Grand Hotel and Convention
Center, Ubonratchathani, Thailand.
|
| |
|
8. |
Chaiyen
P. 2010. The Quest to Explore How Enzymes Work. TRF-CHE-Scopus Researcher Award Lecture at the 10th Thailand Research Fund Annual Meeting, 14-16 October 2010, at Holiday Inn Resort Regent Beach, Cha-am, Petchaburi, Thailand. |
| |
|
9. |
Chaiyen
P. 2010. Mechanistic Studies of Flavin-Dependent and PLP-Dependent Enzymes. Taguchi Prize for Outstanding Research Achievement in Biotechnology 2010 Lecture at International Conference on Biotechnology for Healthy Living. The 22th Annual Meeting of the Thai Society for Biotechnology 20-22 October 2010, at Prince Songkla University, Trang Campus, Thailand.
|
| |
|
10. |
Chaiyen
P. 2011. Exploring the Reaction Mechanism of Pyranose 2-Oxidase Through Transient Kinetics. At the 4rd International Conference for Value Added Agricultural Products on August 29-31, 2011 in Khon Kaen, Thailand.
|
| |
|
11. |
Chaiyen
P. 2011. Understanding the Oxygenation Mechanism of Flavin-Dependent Monooxygenases through a Model of p-Hydroxyphenylacetate Hydroxylase. The 37th Congress on Science and technology of Thailand (STT37), October 12, 2011 at Centara Grand & Bangkok Convention Centre at Central World, Bangkok, Thailand. |